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Biodegradable Duodenum Barrier Implant for Obesity and Glycemic Control

Tsai Hsieh-chih, National Taiwan University of Science and Technology
Year 2017Year Period:2017-12-31 to 2020-03-31

Overview

  • Surgery remains the gold-standard treatment for morbid obesity and diabetes, as well as glycemic control. But the risk and complications of invasive surgery tends to cause patient stress, both physiological and psychological.
  • Reduce intestinal secretion and inhibit absorption to reduce both blood sugar and weight.
  • Enhance patient safety, mitigate complications, keep blood sugar under control, and lower HbA1c.

Development Process

Over the course of this project under the Applied Research Incubation Program, the team completed a prototype, conducted material homogeneity analysis, established an animal test model and verified its safety, and applied for a patent in Europe. The said animal test proved this duodenum barrier implant’s effectiveness in keeping blood sugar under control and lowering HbA1c without causing liver abscess and rejection reaction, thereby establishing its clinical viability and pointing to a rosy future for product development. Also conducted were spin-in consultations and fundraising.

Milestones

2021
  • Incubated in the Biomed Commercialization Center.
2017
  • Admission to the MOST’s Nursery Program
2015
  • Collaborates with National Taiwan University of Science and Technology and Tri-service General Hospital.

Project Leader

Project ManagerJiaru Wu  SpecializationBiomedical materials and biomolecular engineering, bio-membrane R&D, surface modification for medical devices, medical devices regulations and product launch applications: having been certified as a reserve seed consultant for medical devices regulations and for Creo Parametric/AutoCAD competence.
Project Manager Jiaru Wu
Specialization Biomedical materials and biomolecular engineering, bio-membrane R&D, surface modification for medical devices, medical devices regulations and product launch applications: having been certified as a reserve seed consultant for medical devices regulations and for Creo Parametric/AutoCAD competence.
Duty Guidance for teams focusing on biomedical materials; drawing on her academic and professional expertise and understanding of applicable regulations to help academic or research teams commercialize their technologies and bring their products to market