Guidance Recipients

Match would-be startups with local industry, academia, and related institutions

Ultrasound Vortex Technology for Thrombolysis

Yeh Chih-kuang, National Tsing Hua University
Year 2021Year Period: to

Overview

  • Venous thromboembolism (VTE) is a chronic disease. The most promising therapy is catheter-assisted administering of drugs (thrombolytic agents) plus ultrasound treatment. Clinically speaking, however, patients often need to stay in bed for days or even one week. Inconvenient as it is, long-term use of thrombolytic agents also tends to incur intracerebral hemorrhage, strokes, and tissue hemorrhage throughout the body.
  • The team has thus developed a solution that combines ultrasound vortex technology and catheter-assisted drug administering. Ultrasound shearing and pushing helps not only debilitate thrombi but also get thrombolytic agents across more effectively, thereby enhancing thrombolytic efficacy.
  • Enhance thrombolytic efficacy, shorten therapeutic duration, and mitigate such side effects as tissue hemorrhage and strokes.

Development Process

Over the course of this project under the Applied Research Incubation Program, the team verified that it could offer in vitro dissolution efficiency 20-30% superior to rivals. A prototype and animal tests are about to be completed.

Milestones

2021
  • Admission to the MOST’s Nursery Program
  • Won National Innovation Award.
  • Won FITI Innovation & Startup Competition.
  • Won Future Technology Award.

Project Leader

Project ManagerSabrina Wang  SpecializationMolecular biology, signal transduction, microbial model building, protein purification, cancer pathology
Project Manager Sabrina Wang
Specialization Molecular biology, signal transduction, microbial model building, protein purification, cancer pathology
Duty Guidance for teams focusing on IVD kits; drawing on her academic and professional expertise and understanding of applicable regulations to help academic or research teams commercialize their technologies and bring their products to market.